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This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
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Revvity
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Danaher Inc
cy3 conjugated dutp Cy3 Conjugated Dutp, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/cy3+conjugated+dutp/Cy3-dUTP/pmc04456452-499-44-46 Average 96 stars, based on 1 article reviews
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Beyotime
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cy3 ![]() Cy3, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/cy3+conjugated+dutp/Cyanine+3-dUTP/10__1179_slash_174313209x459183-51-7-13 Average 93 stars, based on 1 article reviews
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This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
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Image Search Results
Journal: Frontiers in Aging Neuroscience
Article Title: Lack of Spinal Neuropeptide Y Is Involved in Mechanical Itch in Aged Mice
doi: 10.3389/fnagi.2021.654761
Figure Lengend Snippet: The degeneration of spinal NPY in aged mice. (A,B) Aging down-regulated NPY in the spinal dorsal horn. Six mice in each group, **** P < 0.0001, 2 (3 male and 3 female) versus 24 months (3 male and 3 female), Student’s t -test. (C,D) The distribution of NPY in the spinal dorsal horn of young (C) and aged (D) mice. Scale bar: 100 μm. (E) Quantitative analysis of NPY intensity indicated the degenerated spinal NPY in aged mice compared with the young mice. Nine slices from 3 mice in each group, *** P < 0.001, 2 (2 male and 1 female) versus 24 months (2 male and 1 female), Student’s t -test. (F,G) Colocalized cells (yellow, arrows) by TUNEL (red) and NPY (green) fluorescence in young and aged mice. Scale bar: 50 μm. (H) The number of TUNEL + cells in each dorsal horn of young and aged mice. Nine slices from 3 mice in each group, **** P < 0.0001, 2 (2 male and 1 female) versus 24 months (2 male and 1 female), Student’s t -test. (I) The percentages of TUNEL + cells among NPY + cells in the spinal dorsal horn of young and aged mice. Nine slices from 3 mice in each group, **** P < 0.0001, 2 (2 male and 1 female) versus 24 months (2 male and 1 female), Student’s t -test.
Article Snippet: Sections were washed in a darkroom and then incubated with the mixture of terminal deoxynucleotidyl transferase and Cy3-conjugated dUTP (
Techniques: TUNEL Assay, Fluorescence